RNA-SEQ ANALYSIS OF GENE EXPRESSION PROFILES IN ISOLATED STRIA VASCULARIS FROM WILD-TYPE AND ALPORT MICE REVEALS KEY PATHWAYS UNDERLING ALPORT STRIAL PATHOGENESIS.

Previous work demonstrates that the hearing loss in Alport mice is caused by defects in the stria vascularis.As the animals age, progressive thickening of strial capillary basement membranes (SCBMs) occurs associated with elevated levels of extracellular matrix expression and hypoxia-related gene and protein expression.These conditions render the a

Transparency International estimates that corruption affects competition, hinders the performance of companies, hinders economic development, generates undue costs for people and companies alike, and for a healthy business environment.Efforts are needed from both the public sector and the private one in order to prevent corruption in all its forms

Abstract We show how to combine higgsed topological vertices introduced in [7] with conventional refined topological vertices.We demonstrate that the extended Seal Kit formalism describes very general interacting D5-NS5-D3 brane systems.In particular, we introduce new types of intertwining operators of Ding-Iohara-Miki algebra between different typ

ABSTRACT This AFTER SHAVE BALM DUSK is a systematic review whose objective was to analyze original studies investigating the association of physical activity in the health of men diagnosed with prostate cancer.The databases used were PubMed, Web of Science, Science Direct, Virtual Library Scielo, and Virtual Library of Health.The descriptors used i